Polymarket Re-enters US with Regulated Prediction Markets

Polymarket has re-entered the US market by partnering with fantasy sports leader PrizePicks to launch regulated prediction markets on its platform. The integration uses Polygon-based event contracts to let users wager on sports, entertainment and cultural events. Following a 2022 CFTC settlement and QCEX acquisition, Polymarket ensured compliance and regained access to millions of US fantasy sports users. It will also serve as the designated clearinghouse for DraftKings’ upcoming prediction markets. In 2025 the platform processed billions in trading volume and secured a $2 billion strategic investment from Intercontinental Exchange. Traders should watch regulatory developments, user growth metrics and wash trading probes, as these factors will shape liquidity and price stability in US prediction markets.
Bullish
This partnership and regulatory re-entry will likely be bullish. In the short term, integration with PrizePicks and DraftKings will drive user growth and boost trading volume, enhancing liquidity in prediction markets. Over the long term, CFTC clearance and ICE backing support stable expansion, reducing regulatory risk and fostering institutional partnerships. Traders can expect increased market depth and pricing efficiency, positioning Polymarket at the forefront of US regulated event trading.